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HCV Genotyping Kit

TRUPCR® HCV Genotyping PCR Kit

TRUPCR® HCV Genotyping Kit is an in vitro nucleic acid amplification assay for the qualitative detection of Hepatitis C Viruses (HCV) and differentiation ofgenotypes 1a, 1b, 2 (2a/2b), 3, 4, 5a and 6RNA in human serum or plasma (EDTA) from HCV- infected individual specimens using Real Time PCR System.

HCV Genotype is a predictor of the outcome of anti-HCV therapy with interferon-based treatment regimens. Genotyping also helps to determine treatment. Hence, before starting combination therapy, it is recommended that the genotype of the infecting HCV isolate be determined so that the patient can receive the most appropriate therapy regimen.

  • HCV Genotyping Kit

Advantages of HCV Genotyping :

  • The test allows highly sensitive qualitative detection of all HCV genotypes – Sensitivity of HCV detection – 35 IU/ml.
  • Its multi-tube and multiplex format allows accurate detection and differentiation of all major genotypes i.e.HCV 1a, 1b, 2 (2a/2b), 3, 4, 5a and 6.
  • The test is highly sensitive to detect genotypes in clinical samples with low viral load – Sensitivity of HCV genotyping – 500 IU/ml.
  • The test uses very specific target regions in the HCV genome for improved genotype/subtype identification.
  • Easy workflow with ready-to-use reagents, works on various real-time PCR platforms.
  • All inclusive test: includes cDNA reagents and qPCR reagents with Internal Control.

More About HCV Genotypes – Indian Scenario

In Indian sub-continent Genotype 3 is more prevalent followed by genotype 1, 4 and 6.South India had a higher distribution of HCV genotype 1 followed by genotype 3 and 4, whereas Eastern India and Northeast India genotype 3was predominantly seen. Genotype 4 was seen in higher numbers from South India and genotype 6 was in Eastern and North Eastern region of India.Genotypes prevailing in Northern regions were 3 and 11.

References:

Christdas J, Sivakumar J, David J, Daniel H, Raghuraman S, Abraham P. Genotypes of hepatitis C virus in the Indian sub-continent: A decade-long experience from a tertiary care hospital in South India. Indian J Med Microbiol 2013;31:349-53

Ordering Information:

CAT. NO. PRODUCT CONTENTS
3B253 TRUPCR®HCV Detection & Genotyping Kit 48 Rxn
3B254 TRUPCR®HCV Detection & Genotyping Kit 96 Rxn
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